Celiac Disease

Celiac disease is characterized by the presence of villous atrophy in a jejunal biopsy specimen. The incidence of celiac disease has been estimated to be 0.33-1 %. Wheat, rye, barley and oats contain the gliadin subfraction of gluten, which evoke a powerful immune response in celiac sufferers. The disease is caused by hypersensitivity to gluten, and withdrawal of gluten from the diet cures the patient. Dermatitis herpetiformis is a skin disorder often associated with celiac disease.

Untreated celiac disease can cause osteoporosis, anemia, infertility and neurological disorders. Patients with untreated celiac disease have a 10 times higher risk for malignant intestinal lymphoma.

Celiac Disease Panel*

The detection of gliadin and transglutaminase antibodies together with endomysial IgA antibodies provides a strong tool for identification of patients with celiac disease, and patients with dermatitis herpetiformis (a skin form of celiac disease). Measurement of IgG as well as IgA antibodies is important as IgA deficient individuals (0.25%) have 10 times higher incidence of celiac disease than those with normal IgA production. 2% of patients with celiac disease are deficient in IgA.

Biohit Celiac Disease Panel consists of four ELISA kits:

Anti-Gliadin IgA ELISA Kit
Anti-Gliadin IgG ELISA Kit
Anti-Transglutaminase IgA ELISA Kit
Anti-Transglutaminase IgG ELISA Kit (For research use only)

In the USA: For research use only. Not for use in diagnostic procedures.